產品描述

塔望科技研發的全身體積描記系統（whole-body plethysmograph，WBP）可對清醒自由活動動物呼吸參數進行測量，如呼吸頻率，潮氣量，氣道高反應性測試（Airway hyperresponsiveness，AHR）等。測試過程中，動物可以處于清醒自由狀態，避免了創傷性氣管切開及麻醉的影響，使實驗過程更加簡便，用于呼吸系統模型動物對藥物等反應性研究，呼吸性藥物的藥理和毒理學研究，特別適合于大批量動物快速初篩試驗，適合長期跟蹤研究和重復性篩查。

產品特點

· 不需要做手術，操作簡單

· 可多通道同時監測

· 可在動物在自然狀態下呼吸的研究以及長期跟蹤實驗，適合進行藥物初篩

· 具有藥物氣溶膠霧化模塊

· 具有自動標定功能

· 具有飲水口和食物口，可進行長期連續監測

· 可選配測量心電、血壓、體溫、心率等指標，可與植入式遙測設備聯合使用

· 具有分析軟件，數據可保存至excel或txt格式

可選配的功能模塊

· 同步視頻監測：同步的視頻錄像文件

· 咳嗽檢測：通過軟件自動監測咳嗽事件

· 其它生理指標測量：可在麻醉或清醒狀態下測量心電、血壓、體溫、心率等指標，可與植入式遙測設備聯合使用

檢測參數

Ti：吸氣時間（s）

Te：呼氣時間（s）

PIF：最大吸氣流速（ml/s）

PEF：最大呼氣流速（ml/s）

Volbal：吸氣時間/呼氣時間

F：呼吸頻率（次/min）

Vt：潮氣量（ml）

Mv：分鐘通氣量（ml）

AV：累積體積（ml）

EF50：呼出50%氣量時對應的呼氣流速（ml/s）

EIP：吸氣末暫停時間

EEP：呼氣末暫停時間

TR：松弛時間

PenH：增強呼氣間歇（enhanced pause）

Rpef：相對時間

適用領域

· 各種呼吸疾病研究，如：哮喘、肺纖維化、肺損傷、ARDS、肺癌等

· 安全藥理：藥物對呼吸系統的影響

· 睡眠呼吸：監測動物低通氣、阻塞性呼吸暫停等

· 環境毒理：環境污染物對動物呼吸的影響

· 吸入式毒理：染毒物質對呼吸系統的毒性影響

· 高原醫學：高原環境對呼吸系統的影響

· 其它需要對呼吸參數評價的場合

相關文獻

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